: 
Test Description
The Cyclosporin Levels Test measures the concentration of cyclosporine in the blood to ensure that the drug levels are within the therapeutic range. Cyclosporine is used to suppress the immune system in organ transplant recipients and to treat autoimmune diseases such as rheumatoid arthritis and psoriasis. The test helps healthcare practitioners optimize the dosage to maximize therapeutic effects while minimizing drug toxicity[1][2].
Indications of the Test
The test is indicated for individuals on cyclosporine therapy, especially organ transplant recipients, to prevent organ rejection and minimize the risk of toxicity. It is also used to monitor drug levels in patients with autoimmune diseases to ensure the drug’s effectiveness and safety[1][2][3].
Patient Preparation/Instructions
No special preparation is usually required for this test. However, patients should follow their healthcare provider’s instructions regarding the timing of the test in relation to their medication schedule[1].
Typical Reference Values
Most individuals display an optimal response to cyclosporine with trough whole blood levels ranging from 100 to 400 ng/mL. However, preferred therapeutic ranges may vary depending on the type of transplant, protocol, and comedications. The target trough concentrations vary according to the clinical protocol and the type of allograft, risk of rejection, concomitant immunosuppressive drugs, and toxicity[1][5].
**Turnaround Time**
The typical turnaround time for the Cyclosporin Levels Test is 1-2 days.
**Order This Test**
You can order the Cyclosporin Levels Test from anywhere in Kenya
by clicking the “Order Test” button and adding it to your cart.
Related tests
Tacrolimus level, serum
External resources
[1] CYSPR – Overview: Cyclosporine, Blood https://www.mayocliniclabs.com/test-catalog/overview/35143
[2] Cyclosporine – Testing.com https://www.testing.com/tests/cyclosporine/
[3] Cyclosporine https://www.ncbi.nlm.nih.gov/books/NBK482450/
[4] Laboratory monitoring of cyclosporine levels: guidelines for the dermatologist – PubMed https://pubmed.ncbi.nlm.nih.gov/2277135/
[5] Cyclosporin https://www.rcpa.edu.au/Manuals/RCPA-Manual/Pathology-Tests/C/Cyclosporin
