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Test Description
The Herpes Simplex Virus (HSV) Type 1 and Type 2-specific antibodies test detects IgG-class antibodies in serum, indicating previous exposure to HSV.
The clinical manifestations of HSV infections vary significantly:
- HSV Type 1: Primarily associated with orolabial infections (cold sores) but can also cause genital infections, especially in certain populations.
- HSV Type 2: Mainly responsible for urogenital infections, predominantly affecting adults.
Clinical Conditions Associated with HSV
- Gingivostomatitis: Inflammation of the gums and mouth.
- Keratitis: infection of the cornea, potentially leading to vision loss.
- Encephalitis: severe brain infection.
- Aseptic meningitis: inflammation of the protective membranes covering the brain and spinal cord.
- Neonatal Herpes: Serious infection in newborns, often transmitted during delivery.
- Genital Tract Infections: Commonly caused by HSV type 2.
Indications of the Herpes Simplex Virus (HSV) Type 1- and Type 2-Test
- Determine previous exposure to HSV types 1 and 2.
- Differentiate between HSV type 1 and type 2 infections.
- Assess risks during pregnancy related to congenital HSV disease.
Patient Preparation/Instructions
No specific preparation is required prior to the test. Patients should ensure that blood samples are collected in the appropriate containers.
Typical Reference Values
- Negative Result: Indicates no detectable IgG antibodies for HSV types 1 or 2.
- Positive Result: Indicates previous exposure to either HSV type.
Interpretation of Results
The presence of IgG antibodies indicates previous exposure to either HSV type but does not confirm an active infection. This test should not be used as a primary diagnostic tool for acute infections.
Cautions
- Testing too early after exposure may yield negative results; a repeat test may be necessary after 14 to 21 days.
- IgG testing cannot differentiate between remote infections and current diseases.
This information is crucial for understanding HSV’s impact on health and guiding appropriate clinical management.
Turnaround Time
Results are typically available within 1 to 3 days after specimen collection.
How To Order This Test In Kenya
To order the Herpes Simplex Virus (HSV) Type 1- and Type 2-Specific Antibodies, IgG test, please click the ‘Order Test’ button and add it to your cart.