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Test Description
The Unconjugated Estriol E3 Test is a laboratory test that measures the levels of unconjugated estriol in the blood. Estriol (E3) is a hormone that is produced by the fetoplacental unit during pregnancy. Unconjugated E3 passes through the placenta into the maternal circulation, where it is rapidly converted into glucuronide and sulfate derivatives to facilitate its excretion
Indications of the Test
The Unconjugated Estriol (E3) Test is used as an adjunct biomarker in the prenatal diagnosis of disorders of fetal steroid metabolism, including Smith-Lemli-Opitz syndrome and X-linked ichthyosis.
It is also used to evaluate primary or secondary fetal adrenal insufficiency after excluding other rare single gene including aromatase deficiency and 17 alpha-hydroxylase deficiency
Patient Preparation/Instructions
There is no specific patient preparation required for the Unconjugated Estriol (E3) Test.
Typical reference values
The reference range for the Unconjugated Estriol (E3) Test varies depending on the gestational age of the fetus. The levels of estriol in a pregnant woman’s blood increase steadily throughout pregnancy and most rapidly during the third trimester.
Turn around Time
The turnaround time for the Unconjugated Estriol (E3) Test varies depending on the laboratory performing the test. However, a more rapid turnaround for the test result is possible.
Order This Test
To order the Unconjugated Estriol (E3) Test, click the “Order Test” button and add it to the cart.
