Y-STR Analysis

Y-STR analysis focuses on short tandem repeats (STRs) found on the Y chromosome, which is only carried by male individuals. Y-STRs are often used in forensics, paternity testing, and genealogical DNA testing[3].

Benefits of Y-STR Analysis**:

– Targets male-only DNA
– Can detect male DNA and determine the number of male contributors in a mixture
– Provides highly informative DNA profiles in an additional 21% of cases when combined with autosomal STR testing[2]

Latest Yfiler Plus PCR Amplification Kit

– Contains 27 Y-STR markers and leverages 6-Dye technology
– Helps maximize discrimination capability and provide optimum results when used with the latest generation Applied Biosystems Quantifiler Trio DNA Quantification Kit and STR kit (GlobalFiler PCR Amplification Kit)[1]

Statistical Analysis

– A typical autosomal STR profile may have an expected frequency of occurrence of 1 in every 100 trillion individuals (10^-14), whereas a typical Y-STR profile may occur in 1 in every 1000 individuals (10^-3)[4]
– The counting method and Discrete Laplace formula are used to estimate population frequencies[5]
– Rapidly mutating Y-STRs can differentiate between closely related individuals, such as siblings or father-son pairs, in up to 56.3% of cases compared to 10% with standard Y-STR kits[5]

To order a Y-STR analysis test, click the ‘Order Test’ button and add it to your cart.

Citations:

[1] https://www.thermofisher.com/us/en/home/industrial/forensics/human-identification/forensic-dna-analysis/pcr-amplification-forensic-dna-profiling/y-str-analysis.html
[2] https://www.sakitta.org/resources/docs/SAKI-Y-STR-Testing.pdf
[3] https://en.wikipedia.org/wiki/Y-STR
[4] https://nij.ojp.gov/nij-hosted-online-training-courses/principles-forensic-dna-officers-court/08-mitochondrial-dna-y-str-analysis/y-str-laboratory-analysis/y-str-statistical-analysis
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457770/