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Test Description
The EGFR Mutation Test is a diagnostic test that detects mutations in the EGFR gene in the DNA of tumor cells. The test is used to determine whether a mutation is present in non-small cell lung cancer tumor cells, which can help determine if EGFR-targeted tyrosine kinase inhibitors (TKIs) are an appropriate treatment option[1].
Indications of the Test
The EGFR Mutation Test is used to detect EGFR gene mutations in non-small cell lung cancer tumor cells. Knowing whether a mutation is present in the cells can help determine if EGFR-targeted tyrosine kinase inhibitors (TKIs) are an appropriate treatment option[1][2].
Patient Preparation/Instructions
The EGFR Mutation Test requires a biopsy of the tumor tissue. The test is typically performed on already available tissue from a previous biopsy.
If a new biposy is required, the primary physician will advise on the procedure.
Results of the Test.
The EGFR Mutation Test detects the presence of mutations in the EGFR gene in the DNA of tumor cells, which helps determine the most appropriate treatment.
Turnaround Time
The turnaround time for the EGFR Mutation Test varies depending on the laboratory performing the test. Patients should consult with their healthcare provider or the laboratory for specific information on turnaround time.
Order This Test
To order the EGFR Mutation Test, click the “Order Test” button and add it to the cart. The test requires a biopsy of the tumor tissue, the tissue block will need to accompany the test request.
References
[1] EGFR Mutation Testing – Testing.com https://www.testing.com/tests/egfr-mutation-testing/
[2] EGFR and Lung Cancer https://www.lung.org/lung-health-diseases/lung-disease-lookup/lung-cancer/symptoms-diagnosis/biomarker-testing/egfr
[3] EGFR Mutation Analysis by PCR https://neogenomics.com/test-menu/egfr-mutation-analysis-pcr
[4] cobas® EGFR Mutation Test v2 | Roche Molecular Diagnostics https://diagnostics.roche.com/us/en/products/params/cobas-egfr-mutation-test-v2.html
[5] EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582044/
