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Test Description
This test measures the levels of anti-glutamic acid decarboxylase (GAD) antibodies in the blood. GAD antibodies are formed against the GAD enzyme, which is responsible for converting glutamate to GABA, a neurotransmitter that inhibits nerve cells. The presence of high anti-GAD antibody titers is associated with various neurological syndromes, such as stiff-person syndrome (SPS), cerebellar ataxia, and other neurological disorders.
Indications of the Test
The test is used to diagnose and monitor patients with anti-GAD antibody-related syndromes, such as stiff-person syndrome (SPS), cerebellar ataxia, and other neurological disorders. It can also help differentiate between these syndromes and other atypical or non-specific neurological disorders.
Patient Preparation/Instructions
There are no specific patient preparation instructions for this test. However, it is essential to consult with a healthcare professional to determine if the test is appropriate for the patient’s clinical presentation.
Typical Reference Values
The normal range for anti-GAD antibody titers is generally considered to be less than 5 U/mL. Titers above 10,000 IU/mL are diagnostic for a true GAD-related syndrome, while lower titers (<10,000 IU/mL) are associated with atypical or non-specific neurological disorders.
Turn Around Time
The turn around time for this test may vary depending on the laboratory and the specific testing method used. It is essential to consult with the laboratory for their turn around time policy.
Order This Test
To order this test, please click the ‘Order Test’ button and add it to the cart. In Nairobi, you can come to our laboratory for sample collection or we can send you to our partner location.
